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在动物模型中Olaparib和Regorafenib之间的药理动力相互作用

Danuta Szkutnik-Fiedler1, Agnieszka Karbownik1, Filip Otto1

  • 1Department of Clinical Pharmacy and Biopharmacy, Poznań University of Medical Sciences, Rokietnicka 3, 60-806 Poznań, Poland.

Pharmaceutics
|January 8, 2025
PubMed
概括

当Olaparib (OLA) 和regorafenib (REG) 同时使用时显著相互作用,在老鼠中改变彼此的药理动力学. 这项临床前研究强调了OLA和REG一起使用时对药物安全的潜在临床相关性.

关键词:
药物 药物相互作用这就是Olaparib.药物动力学 药物动力学鼠类 鼠类 鼠类 鼠类 鼠类雷戈拉芬尼布的使用情况

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