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Updated: Jun 3, 2025

PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS
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双螺丝化粒度的Simvastatin:使用聚合物混合物提高药物可溶性和溶解率

Rasha M Elkanayati1, Indrajeet Karnik1, Prateek Uttreja1

  • 1Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA.

Pharmaceutics
|January 8, 2025
PubMed
概括

双螺旋融颗粒化 (TSMG) 和热挤出 (HME) 使用聚合物混合物显著改善了simvastatin (SIM) 的溶解性和溶解性. 该SIM-SOP/KIR配方显示,可溶性增强了5.5倍,并迅速释放药物.

关键词:
科利科亚特 IR 的位置这就是Soluplus.无形固体分散的无形固体分散热挤出方式混杂性 混杂性 混杂性水溶性较差的药物药物.可溶性增强 提高可溶性双螺丝融化颗粒化

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