使用光电显微学方法进行外周血动力学估计
Toru Shimuta1, Kaname Hanada1, Kazuteru Ryu2
1Minato MIRAI Innovation Center, Murata Manufacturing Co., Ltd., 4-3-8, Minatomirai, Nishi-ku, Yokohama-shi 220-0012, Japan.
Sensors (Basel, Switzerland)
|January 8, 2025
概括
一个新的环形可穿戴设备使用光聚聚光学来轻松测量糖尿病患者血液循环的日常变化. 这项技术有助于估计外围血液动力学,有助于在家进行健康监测.
科学领域:
- 生物医学工程 生物医学工程
- 医疗器械 医疗器械
- 心血管生理学心血管生理学
背景情况:
- 糖尿病与毛细血管和动脉小血管的外周血液循环受损有关.
- 目前用于糖尿病患者每日监测微血管功能的方法有限.
- 摄影透视图 (PPG) 提供了一种潜在的非侵入性方法来评估血液流动动力学.
研究的目的:
- 开发和评估一款用于测量手指光电流图 (PPG) 的新型环戴设备.
- 评估使用该设备用于糖尿病患者周围血液动力学每日监测的可行性.
- 为了比较糖尿病患者和健康对照组之间的PPG参数.
主要方法:
- 开发一种基于手指的PPG设备,使用绿色和近红外LED.
- 招募25名糖尿病患者和21名健康成年人作为对照组.
- 获取和分析PPG信号,包括在半最大速度和波峰定时时的逆全宽.
主要成果:
- 与对照人群相比,糖尿病患者在半最大速度的胸膜图上表现出较小的逆全宽的趋势.
- 在糖尿病患者中,与近红外光a波峰相比,绿光a波峰的延迟显著增加.
- 这些发现表明糖尿病患者的周围血液动力学特征发生变化.
结论:
- 开发的环戴式PPG设备可以有效地测量手指光电流图.
- 与糖尿病相关的外周血液动力学变化可以通过使用该设备进行非侵入性估计.
- 这项技术有望在家中方便地每天监测糖尿病患者的循环健康.
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