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在移植中的抗病毒管理

Sruthi Bonda¹, Sonya Trinh¹, Jonathan Hand^1,2

¹Department of Infectious Diseases, Ochsner Medical Center, New Orleans, LA 70115, USA.

|January 8, 2025

概括

对移植患者来说,抗病毒管理计划 (ASP) 对于治疗病毒感染至关重要. 本综述探讨了抗病毒管理 (AVS) 的关键机会,以改善对这些脆弱个体的护理.

科学领域:

传染性疾病传染性疾病
移植医学移植医学移植医学
药理学药理学是指药理学的学科.

背景情况:

抗菌药物管理计划 (ASP) 是医院的任务,但移植接受者的参与是有限的.
对移植患者的最佳抗病毒管理 (AVS) 实践仍未确定.
病毒感染在移植受体中存在重大风险,包括发病率和死亡率.

研究的目的:

审查和强调移植受体中抗病毒管理 (AVS) 的机会.
为了应对这种人群中管理病毒感染的具体挑战.
为移植护理相关的各种病毒提供有关AVS的见解.

主要方法:

专注于抗病毒管理干预措施的文献综述.
对细胞巨型病毒 (CMV),爱斯坦-巴尔病毒 (EBV),简单性疹病毒 (HSV),疹病毒 (VZV),SARS-CoV-2,呼吸道同胞性病毒和BK多重性瘤病毒的AVS策略的分析.
检查AVS的临床综合征,诊断,耐药性和经济因素.

主要成果:

在移植患者中确定了针对多种病毒的特定AVS机会.
强调了AVS的重要性,因为与病毒感染相关的高风险.
讨论了包括药物毒性和耐药性在内的挑战.

结论:

抗病毒管理对于优化移植受体的护理和结果至关重要.
有针对性的AVS干预可以减轻病毒感染的影响.
对这个患者群体需要进一步的研究和AVS协议的实施.

关键词:

抗微生物药物管理管理抗病毒管理的管理.细胞巨型病毒 (cytomegalovirus) 是一种病毒.呼吸道同胞性病毒

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