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Updated: Jun 3, 2025

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
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使用M184V的提米丁模拟突变显著降低HIV-1亚型C逆转录酶对伊斯拉特拉维尔的表型敏感性

Hyeonah Byun1, Maria Antonia Papathanasopoulos1, Kim Steegen2,3

  • 1HIV Pathogenesis Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa.

Viruses
|January 8, 2025
PubMed
概括

伊斯拉特拉维尔对常见的HIV-1亚型C核酸逆转录酶抑制剂耐药性突变显示出有效性. 然而,涉及M184V与蒂米丁模拟突变的组合可能会降低敏感性,影响治疗策略.

关键词:
艾滋病病毒 艾滋病病毒 艾滋病病毒这就是为什么NRTI是NRTI.抗逆转录病毒治疗 (ART)抗病毒药物 抗病毒药物药物耐药性 耐药性 药物耐药性伊斯拉特拉维尔 (ISL) 是一种现象型的表型C亚型的C亚型是C亚型的

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