较高的飞机噪音暴露与更糟糕的心脏结构和功能有关,通过心血管MRI
Constantin-Cristian Topriceanu1, Xiangpu Gong2, Mit Shah3
1UCL MRC Unit for Lifelong Health and Ageing, University College London, London, United Kingdom; UCL Institute of Cardiovascular Science, University College London, London, United Kingdom; Cardiac MRI Unit, Barts Heart Centre, London, United Kingdom.
Journal of the American College of Cardiology
|January 8, 2025
概括
暴露于飞机噪音与不良的左心室重塑有关,增加了主要不良心脏事件的风险. 这种重塑可能是由噪音引起的肥胖和高血压驱动的.
科学领域:
- 环境健康 环境健康
- 心血管医学 心血管医学
- 医疗成像医学成像
背景情况:
- 对于靠近机场的社区来说,飞机噪音是一个重要的环境问题.
- 越来越多的证据表明,环境噪音和不良健康结果之间存在联系.
研究的目的:
- 研究飞机噪音对心脏结构和功能的影响.
- 探索心血管风险因素和下游临床影响的潜在调解.
主要方法:
- 利用英国生物库数据和心血管磁共振 (CMR) 成像,对在英国主要机场附近的参与者进行成像.
- 评估了夜间 (Lnight) 和昼夜 (Lden) 飞机噪音水平与CMR衍生心脏指标之间的关联.
- 采用了通用线性模型,并探索了BMI和高血压等风险因素的调解.
主要成果:
- 较高的夜间飞机噪音暴露与左心室 (LV) 质量和壁厚度的增加有关,这表明LV重塑不利.
- 噪音暴露与LV心肌动力学受损相关,包括减少全球周围应变.
- 肥胖和高血压被确定为调解因素,解释了10-50%的观察到的关联.
结论:
- 暴露于飞机噪音与心脏结构和功能的有害变化有关.
- 这些心脏变化可能会增加主要心脏不良事件 (MACE) 的风险.
- 调查结果强调,政策制定者和航空业需要解决飞机噪音对心血管健康的影响.
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