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Updated: Jun 3, 2025

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连接体和残留物自由能量扰乱解决了A2BAR部分激动剂的双结模式建议

Tana Tandarić1, Hugo Gutiérrez-de-Terán1,2

  • 1Department of Cell and Molecular Biology, Biomedical Center, Uppsala University, Box 596, Uppsala SE-75124, Sweden.

The journal of physical chemistry. B
|January 8, 2025
PubMed
概括

计算模拟澄清了部分激动剂BAY60-6583与腺A2B受体 (A2B AR) 的结合模式. 这一发现有助于设计改进的A2B AR向治疗方法,用于诸如癌症免疫疗法等疾病.

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