静止的呼吸器长期促进增加了对后续运动呼吸器反应的前贡献
Joseph F Welch1, Brighton R Cretney1,2, Gordon S Mitchell3
1School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
Journal of applied physiology (Bethesda, Md. : 1985)
|January 8, 2025
概括
由急性间歇性缺氧 (AIH) 引起的呼吸神经可塑性,增强了运动通风. 这种休息诱导的可塑性改变了运动期间的呼吸反应,改善了CO2调节.
科学领域:
- 呼吸系统生理学 呼吸系统生理学
- 神经科学是一个神经科学.
- 运动生理学 运动生理学
背景情况:
- 呼吸控制系统表现出神经可塑性,根据先前的刺激来调整呼吸控制.
- 了解休息呼吸系统可塑性如何影响运动通风对于呼吸控制研究至关重要.
研究的目的:
- 为了测试休息时因超性急性间歇性缺氧 (AIH) 引起的呼吸器长期促进 (LTF) 是否在稳定状态炼期间增强了随后的呼吸器反应.
- 调查AIH诱导的LTF对炼性呼吸过敏,系统增益和终潮PCO2调节的影响.
主要方法:
- 14名健康成年人接受了肺功能测试.
- 参与者暴露于AIH (15,1分钟低氧期与室内空气间隔) 或Sham条件.
- 在AIH/Sham.Sham期间和之后,轻度的头增大仍然存在. 干预后测量了对稳定状态循环运动 (30,60,90 W) 的呼吸器反应.
主要成果:
- 与Sham相比,AIH诱导了显著的呼吸系统长期促进 (LTF).
- 虽然运动期间的每分钟通风没有显著差异,但在AIH后,通风/CO2生产关系 (系统增益) 和前运动增益显著增加.
- 与Sham相比,在AIH之后的所有炼工作负载中,潮尾PCO2的调节率较低.
结论:
- 通过超性AIH在休息时诱导的呼吸机可塑性会在轻度至中度稳定状态运动期间改变随后的呼吸机反应.
- 由AIH诱导的LTF增加了运动过呼吸的前成分,并改善了运动期间的潮末PCO2控制.
- 静止状态下的呼吸机运动可塑性可以影响其他条件下的生理反应,例如运动.
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