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Updated: Jun 3, 2025

Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations
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Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations

Published on: July 24, 2021

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针对格拉姆阳性细菌感染的抗生素候选药物诱导多药性耐药性

Ana Martins1,2, Fanni Judák1,3, Zoltán Farkas1

  • 1Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre Szeged, Szeged HU-6726, Hungary.

Science translational medicine
|January 8, 2025
PubMed
概括

黄金葡萄球菌对新药候选物的抗生素耐药性很容易发展. 细菌中先前存在的遗传变异可能会加速耐药性,影响未来的抗生素开发和临床使用.

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