人类便微生物群移植的营养优化:一个范围审查
Levi M Teigen1, Austin Hoeg2, Hijab Zehra1
1Department of Food Science and Nutrition, University of Minnesota, St. Paul, MN, USA.
Gut microbes
|January 8, 2025
概括
饮食显著影响肠道微生物群,可以优化便微生物群移植 (FMT) 治疗. 本综述探讨了围绕FMT的饮食摄入量,确定差距,并提出精确营养策略,以提高治疗的有效性.
科学领域:
- 微生物组研究的研究.
- 营养科学 营养科学
- 胃肠病学 胃肠病学
背景情况:
- 饮食是肠道微生物组成和功能的主要驱动因素.
- 便微生物群移植 (FMT) 是对各种疾病的有希望的治疗方法,但其优化能力有限.
- 饮食在调节FMT疗效方面的作用经常被忽视.
研究的目的:
- 进行人类研究的范围审查,检查FMT前后的饮食摄入量.
- 确定有关饮食和FMT的研究差距.
- 为未来关于基于FMT的精密营养研究提出建议.
主要方法:
- 在五个数据库中进行全面的文献搜索.
- 纳入标准:对成人进行任何指示的FMT的研究,重点是饮食摄入量 (包括食物和补充剂).
- 选了7721篇文章,其中18篇符合纳入标准.
主要成果:
- 确定了关于FMT前后饮食摄入量的异质文献.
- 制定了一个针对FMT捐赠者和接受者的营养考虑的框架.
- 突出了精准营养策略的机会,以改善FMT的临床结果.
结论:
- 饮食干预是优化FMT的重要,未得到充分利用的策略.
- 需要进一步的研究,以建立基于证据的,个性化的 FMT 营养指南.
- 开发基于FMT的精密营养可以提高治疗效果.
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