NAFLD和肝纤维化与基于NHANES 2017-2018年营养风险指数的营养风险指数之间的关联
Jieming Jian1, Rui Zhang1, Yuan Dong1
1Department of Endocrinology, Translational Research of Diabetes Key Laboratory of Chongqing Education Commission of China, the Second Affiliated Hospital of Army Medical University, Chongqing, 400037, China.
Lipids in health and disease
|January 8, 2025
概括
营养风险指数 (NRI) 与非酒精性脂肪肝疾病 (NAFLD) 和肝纤维化有积极的关联. 炎症可能部分介导NRI和NAFLD之间的联系,突出营养营养.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 非酒精性脂肪肝 (NAFLD) 和肝纤维化与营养和炎症有关.
- 营养风险指数 (NRI) 评估营养状况,但其在NAFLD和纤维化中的作用尚不清楚.
研究的目的:
- 调查营养风险指数 (NRI) 与非酒精性脂肪性肝病 (NAFLD) 和肝纤维化之间的关联.
- 探索NRI与这些肝脏疾病之间的关系中炎症的调解作用.
主要方法:
- 利用了2017-2018年国家健康和营养检查调查的数据.
- 采用后勤回归,限制立方线 (RCS) 和调解分析来评估关联和炎症的作用.
主要成果:
- 在NAFLD和肝纤维化患者中观察到较高的NRN水平.
- NRI显示与NAFLD和肝纤维化的几率有积极的关联.
- 炎症部分介导了NRI和NAFLD之间的关联.
结论:
- 营养风险指数 (NRI) 可能是NAFLD和肝纤维化的潜在相关标志物.
- 营养状况对于这些肝病的发展至关重要.
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