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Updated: Jun 3, 2025

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications
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Published on: January 27, 2014

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新型阿克里衍生物作为潜在的P2Y12受体抑制剂:整合计算建模和实验分析

Fadi G Saqallah1, Belal O Al-Najjar2,3, Aya Y Al-Kabariti2,3

  • 1Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan.

Journal of biomolecular structure & dynamics
|January 8, 2025
PubMed
概括

研究人员探索了针对急性心肌梗塞的新型P2Y12抑制剂. 计算建模和体外试验确定NSC380324和NSC618163是有希望的候选物,显示出显著的P2Y12活动抑制.

关键词:
抗血小板药物是一种抗血小板药.在P2Y12中,P2Y12在P2Y12中.在Cangrelor,我们可以看到Cangrelor.分子动力学分子动力学血管扩散剂刺激的蛋白酸化

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A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 406:56

A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4

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