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在SARS-CoV-2感染中,CXCL12改善了中性恋和疾病严重程度

Jian Zheng1,2,3, Hima Dhakal1, Enya Qing4

  • 1Department of Microbiology and Immunology and.

The Journal of clinical investigation
|January 8, 2025
PubMed
概括

中性粒细胞数量在SARS-CoV-2感染期间和之后增加. 阻止化学物质CXCL12意外地恶化了小鼠的COVID-19结果,突出了它在疾病严重性中的复杂作用.

关键词:
在 COVID-19 疫情中,化学因子 (chemokines) 是一种化学物质.内皮细胞是内皮细胞.传染病 传染病是一种传染病.中性粒细胞中性粒细胞.

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Coronaviruses, including the severe acute respiratory syndrome coronavirus (SARS-CoV), are enveloped viruses characterized by their single-stranded, positive-sense RNA genome and helical nucleocapsid structure. The hallmark of these viruses is their club-shaped spike (S) glycoproteins that protrude from the viral envelope, facilitating attachment to host cells. Typically, coronaviruses infect the upper respiratory tract, often causing mild or asymptomatic disease. However, certain strains like...