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Updated: Jun 3, 2025

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综合应激反应驱动MET在癌症中的癌基因过度表达

Marina Cerqua1, Marco Foiani1, Carla Boccaccio2,3

  • 1IFOM ETS-The AIRC Institute of Molecular Oncology, 20139, Milano, Italy.

The EMBO journal
|January 8, 2025
PubMed
概括

癌细胞通过综合应激反应 (ISR) 过度表达MET瘤基因,这是由MET mRNA 5'未翻译区域 (5'UTR) 调节的过程. 阻止这种压力诱导的MET转化抑制了癌症的入侵.

关键词:
综合应激反应综合应激反应侵袭性生长 侵袭性生长在市场营销条件下对瘤基因进行治疗.

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