墨西哥社会保障人口中人类感染mopox的危险因素
Alfonso Vallejos Parás1, Lumumba Arriaga Nieto1, David Alejandro Cabrera Gaytán2
1Epidemiologic Surveillance Coordination, Mexican Institute of Social Security, Mexico City, Mexico.
PloS one
|January 8, 2025
概括
2022年的mopox疫情影响了80多个国家,墨西哥的累计发病率为每10万人4.05. 男性,与男性发生性关系的男性和艾滋病毒感染者中,Mopox风险更高.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 2022年mopox疫情代表了这一动物传播疾病流行病学的全球转变.
- 病例迅速蔓延到80多个非流行国家,导致全球病例超过7万.
研究的目的:
- 为了量化墨西哥mopox的累积发病率.
- 在2022-2023年爆发期间,在墨西哥社会保障研究所附属人口中确定与mopox感染相关的因素.
主要方法:
- 进行了一项回顾性,横截面的观察性研究.
- 累积发病率是按每10万个人计算的,并根据人口统计和艾滋病毒状况进行分析.
- 后勤回归确定了mopox感染的社会人口统计和临床预测因素.
主要成果:
- 在2,956个可能的病例中,实验室确认了1,744个mopox病例.
- 累计发病率为每10万人4.05,男性和与男性发生性关系的男性 (MSM) 的发病率更高.
- 男性,30-44岁,MSM和艾滋病毒感染者均有显著更高的POPOX风险. 发烧,手臂皮疹和 inguinal lymphadenopathy 是关键的临床预测因素.
结论:
- 2022年mopox疫情突出了感染风险的重大差异.
- 男人,MSM和艾滋病毒感染者面临不成比例的更高风险.
- 了解这些差异对于有针对性的公共卫生干预至关重要.
相关概念视频
Factors Affecting the Risk of Infection
11.3K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.3K
Mismatch Repair
4.8K
Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
4.8K
Infection
7.6K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
7.6K
Pulmonary Tuberculosis I
220
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
220
Skin Diseases and Disorders
2.9K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
2.9K


