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左心室透静功能障碍很普遍,但与败血性休克患者的死亡率无关

Philippe Vignon^1,2,3, Cyril Charron⁴, Annick Legras⁵

¹Medical-Surgical ICU, Dupuytren University Hospital, Réanimation Polyvalente, CHU Dupuytren, Limoges, France. philippe.vignon@unilim.fr.

Intensive care medicine

|January 8, 2025

概括

左心室扩张性功能障碍 (LVDD) 在败血性休克中很常见,但不会影响死亡率. 在三分之一的幸存者中,LVDD显示改善,这表明它不是一个显著的预后因素.

科学领域:

心脏病学心脏病学
密集护理医学密集护理医学
心声回声扫描 (Echocardiography) 是一种心声回声扫描.

背景情况:

左心室扩张功能障碍 (LVDD) 是心血管疾病中常见的发现.
它在严重疾病 - - 败血性休克的预后意义尚不清楚.
目前对LVDD的诊断指南尚未在败血症休克患者中得到充分评估.

研究的目的:

为了确定LVDD在败血症休克患者的预后影响.
评估ICU入院前3天内LVDD与28日死亡率之间的关系.
用当前的诊断指南来评估LVDD.

主要方法:

对402名败血症休克患者 (败血症-3定义) 的前性,多中心的观察性研究.
在ICU入院12小时内对LVDD进行心声检查,在ICU退院的第二天,3日和28日进行心声检查.
利用2016年美国 - 欧洲指南用于LVDD诊断.

主要成果:

LVDD的患病率很高,在76%的患者中至少在第一到第三天之间检测到一次.
28日死亡率在LVDD患者和没有LVDD患者之间没有统计学上显著的差异 (26%对28%).
在随访后,34%的患者的LVDD有所改善,49%的改善患者的LVDD完全回归.

结论:

在败血症休克中,LVDD非常普遍,但与28日死亡率没有独立关联.
浸泡功能可能会改善在性休克的过程中幸存者.
根据目前的发现,LVDD不是在败血性休克患者中可靠的预后标志物.

关键词:

左心室的扩张功能.预测预后预测预测败血症这是一种败血症.败血症的冲击是一个令人震惊的结果.

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