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在泰国南部的被动监控系统中持续检测到奇孔古尼亚病毒,2012-2019年

Aaron Farmer¹, Kathryn B Anderson^1,2, Darunee Buddhari¹

¹Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.

PLoS neglected tropical diseases

|January 8, 2025

概括

奇孔古尼亚病毒 (CHIKV) 感染在全球范围内导致长期疾病. 这项在泰国的研究发现了持续的CHIKV循环,感染率在2018-2019年爆发期间达到顶峰,这表明正在进行的传播风险.

科学领域:

* 医学昆虫学医学昆虫学
* 传染病传染病
* 流行病学流行病学

背景情况:

* 奇孔古尼亚病毒 (CHIKV) 导致全球显著的发病率与不可预测的传播模式,复杂的疫苗评估.
*爆炸性流行病是CHIKV疫情的特征,间隔有变化的流行间时期.

研究的目的:

* 调查在泰国南部持续传播的奇孔古尼亚病毒.
* 分析随着时间的推移,发烧个体中CHIKV感染的流行率.

主要方法:

*从2012年到现在,在泰国南部对未分化的发烧性疾病的被动监测.
*对1466名发烧患者的急性和康复样本进行分子和血清学检测.
* 分析每年的CHIKV感染比例.

主要成果:

* 在1466名 (27.1%) 个体中,有398人显示出急性CHIKV感染的证据.
*CHIKV感染患病率因年而异,在2018-2019年流行期间 (41.1%) 与2012-2017年 (19.3%) 相比显著上升.

结论:

* 数据表明,研究区域中 Chikungunya 病毒的循环持续存在.
*需要进一步的研究来证实这些发现,并区分广泛的低水平传播和焦点流行病活动.

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