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Updated: Jun 3, 2025

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通过 κ-阿片类受体-G 蛋白质复合体的逆激素的分子机制

Aaliyah S Tyson1,2, Saif Khan1,3, Zenia Motiwala1,3,4

  • 1The Bridge Institute, Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA.

Nature chemical biology
|January 8, 2025
PubMed
概括

某些卡帕阿片类受体 (KOR) 反向激素激活了G蛋白信号传递,而没有激素. 这挑战了对G蛋白结合受体 (GPCR) 反对性的传统理解,并揭示了新的药理学见解.

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