基于自然的内解决方案的抗菌疗效:通过网络元分析进行系统审查
Danilo Cassiano Ferraz1, Anahi de Paula Melo1, Felipe de Souza Matos2
1Universidade Federal de Uberlândia - UFU, School of Dentistry, Postgraduate Program in Dentistry, Uberlândia, MG, Brazil.
Brazilian oral research
|January 8, 2025
概括
天然内牙溶液 (NES) 显示了对Enterococcus faecalis.的抗菌潜力. 虽然没有超过酸盐 (NaOCl),但果与NaOCl结合的果在根运河灌中显示出显著的细菌减少.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 微生物学 微生物学
- 生物材料是一种生物材料.
背景情况:
- 菌 (Enterococcus faecalis) 是牙周内感染的持续性病原体.
- 传统的灌剂,如低化 (NaOCl) 和氧化 (CHX) 是有效的,但有局限性.
- 自然内牙解决方案 (NES) 正在作为替代品或辅助品进行探索.
研究的目的:
- 系统地审查和比较NES对Enterococcus faecalis的临床前抗菌疗效.
- 评估NES与NaOCl和CHX结合或作为根管灌中的替代品.
主要方法:
- 按照PRISMA指南进行系统审查和网络元分析.
- 包括模拟根管灌的ex vivo研究.
- 殖民地形成单位 (CFU) 在灌前后进行评估.
主要成果:
- 与2.5%的NaOCl相结合的果显示了减少CFU的最高概率.
- 2%的CHX和NaOCl也显示出显著的CFU减少.
- 对偏见风险的评估表明,在几项研究中,报告遗漏.
结论:
- 对于Enterococcus faecalis.alis.来说,NES具有抗菌潜力.
- NES,特别是含有NaOCl的果,是有前途的,但不能超过单独的NaOCl.
- 由于发现了报告缺陷,需要进一步进行高质量的研究.
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