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巴西南部口腔潜在恶性疾病的时间流行病学概况
Natália Souza Dos Santos1, Amanda Zimmer Rodrigues1, Camila Alves Ferri1
1Universidade Federal do Rio Grande do Sul - UFRGS, School of Dentistry, Deppartment of Oral Pathology, Porto Alegre, RS, Brazil.
Brazilian oral research
|January 8, 2025
概括
口腔潜在恶性疾病 (OPMDs) 在妇女和高风险地区正在增加. 白血球皮质增生症和发育不良症表明恶性转变风险较高,强调位置和预防的特征.
科学领域:
- 口腔病理学 口腔病理学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 口腔潜在恶性疾病 (OPMDs) 是一个重要的公共卫生问题,因为它们有可能恶性转变.
- 了解与OPMD相关的长期趋势和风险因素对于有效的预防和管理策略至关重要.
- 需要对几十年来OPMD数据进行全面分析,以确定不断变化的模式并改善临床结果.
研究的目的:
- 为了调查在巴西南部口腔病理学服务中诊断的OPMD的56年发生率和特征.
- 确定影响OPMD严重程度和恶性转变风险的因素.
- 评估OPMD发生的时间趋势,特别是关于性别和解剖位置.
主要方法:
- 从1965年到2021年,对689个OPMD组织病理记录进行了回顾性分析.
- 纳入标准:白血病,红血病,白血病,白血病,行动性脑炎.
- 收集的数据:患者人口统计,风险行为,临床表现,活检细节,病原体诊断和随访信息.
主要成果:
- OPMD占所有组织病理学报告的2.10%,主要影响51岁以上的男性,通常在低风险地区.
- 随着时间的推移,在女性和高风险解剖部位中观察到OPMD的发病率增加.
- 恶性转变发生在9.6%的病例中,平均随访时间为30.28个月,白血红细胞增生和上皮质形显示出更高的风险,特别是在高风险部位.
结论:
- 临床和显微特征,以及解剖位置,对于评估OPMD恶性转变风险至关重要.
- 在女性和高风险地区观察到的OPMD的增加需要有针对性的公共卫生干预措施.
- 这些发现有助于临床医生管理OPMD,并有助于改善口腔癌预防策略.
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