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Updated: May 6, 2026

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布普伦诺芬:一个以麻醉为中心的审查.

Thomas Hickey1, Gregory Acampora2

  • 1Anesthesiology, Yale University School of Medicine; VA Connecticut Healthcare System, New Haven, Connecticut. ORCID: https://orcid.org/0000-0003-4890-0238.

Journal of opioid management
|January 8, 2025
PubMed
概括

布普伦诺啡因为治疗急性和慢性疼痛提供了一种有效的替代品,可以替代完全激动性阿片类药物. 现在在手术期间继续使用布普伦诺啡是首选的,尽管最佳剂量需要进一步研究.

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Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
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Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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