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Updated: Jun 3, 2025

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在人类癌症中对mRNA与蛋白质表达的突变影响

Yuqi Liu1, Abdulkadir Elmas1, Kuan-Lin Huang1

  • 1Department of Genetics and Genomic Sciences, Department of Artificial Intelligence and Human Health, Center for Transformative Disease Modeling, Tisch Cancer Institute, Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

GigaScience
|January 8, 2025
PubMed
概括

身体突变可以影响癌症蛋白质水平不同于基因水平. 这项研究使用蛋白质基因组学来发现对蛋白质丰度有明显影响的突变,有助于识别关键癌症驱动因素.

关键词:
蛋白质基因组学是什么癌症突变 癌症突变蛋白质表达 蛋白质表达定量特征位置 (QTL)变种效应是变种效应的影响.

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