巴西透析中心的多中心研究:SARC-HD研究的招聘和实施
Marvery P Duarte1, Otávio T Nóbrega1, Barbara P Vogt2
1Universidade de Brasília, Faculdade de Ciências da Saúde, Brasília, DF, Brazil.
Jornal brasileiro de nefrologia
|January 8, 2025
概括
巴西透析中心的多中心研究是可行的,正如SARC-HD研究表明的那样.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床研究 临床研究
- 流行病学 流行病学
背景情况:
- 在巴西的透析中心,多中心研究举措是罕见的.
- 这项SARC-HD研究旨在研究血清透析患者的萨科佩尼亚及其临床结果.
- 这项研究侧重于大型队列研究的招聘和实施阶段.
研究的目的:
- 描述SARC-HD研究的招聘和实施过程.
- 确定在研究的初始阶段遇到的障碍和促进因素.
- 评估巴西透析机构中多中心研究的可行性.
主要方法:
- 一项涉及巴西血液透析患者的队列研究.
- 定义了招聘和实施阶段,随后收集调查员反.
- 使用一个结构化问卷,主要的研究人员收集关于研究过程的见解.
主要成果:
- 21个中心最初同意,有19个参与;10个主要调查员管理了19个地点.
- 实现了66.1%的招募率,在1525名查患者中招募了1008名患者.
- 确定了研究基础设施/物流作为障碍,指导委员会管理作为促进者;通过特定问卷记录了数据收集的挑战.
结论:
- 招募和实施多中心SARC-HD研究是可行的.
- 确定障碍物和促进者可以在临床环境中为未来的多中心研究提供信息.
- 将研究纳入临床例行程序对于成功的多中心计划至关重要.
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