患有慢性脏疾病的患者中与性的发展相关的危险因素:系统性审查
Cyprian O Ogah1, Huda Mohammed2, Ingie M Gabra3
1Internal Medicine, Valley Baptist Medical Center Harlingen, Harlingen, USA.
Cureus
|January 8, 2025
概括
透析是发烧结核病的主要危险因素,这是一种严重的疾病,影响病患者. 其他因素包括白人种族,女性性别,肥胖,糖尿病和某些药物.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 皮肤病学 皮肤病学
- 血管生物学 血管生物学
背景情况:
- 石灰症或石灰尿性动脉动脉病 (CUA) 是一种罕见的,高死亡率的疾病.
- 病原发生涉及酸失调和动脉结石化,主要是在慢性病 (CKD) 患者.
- 现有的文献缺乏结构化的风险分析,重点是诊断/治疗,而不是风险因素.
研究的目的:
- 系统地审查和识别慢性病患者中状发育的危险因素.
- 为了弥补对石灰症风险因素的实验和系统审查的差距.
- 为了提供一个基础,在calciphylaxis结构化风险概况.
主要方法:
- 用关键词对电子数据库 (2018-2024) 进行系统审查:石灰症,慢性病,危险因素.
- 纳入/排除标准适用于486个已识别的产品;进行了质量评估.
- 从16篇符合条件的文章中提取数据,涉及1739名患者.
主要成果:
- 透析成为化症最常见的危险因素.
- 其他已识别的危险因素:高加索族裔,女性性别,肥胖,糖尿病,副甲状腺激素升高,以及使用维生素K对抗剂,维生素D和酸结合剂.
- 审查的研究主要是观察性的,通常是以小样本大小为中心的单一研究.
结论:
- 透析是慢性病患者化症的重要危险因素.
- 多种人口统计和临床因素有助于结石症的风险.
- 建议进行大规模的多中心研究,以建立可靠的石灰症风险概况.
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