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Updated: Jun 3, 2025

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
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基于生物功能材料的工程神经导管用于视神经再生:从细胞角度看,挑战和未来前景

Enoch Obeng1,2, Baoguo Shen1,2, Wei Wang1,2

  • 1State Key Laboratory of Ophthalmology, Optometry and Vision Science, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.

Regenerative biomaterials
|January 8, 2025
PubMed
概括

了解视神经再生对于治疗视力丧失至关重要. 这篇评论探讨了细胞和分子机制以及神经导管应用,以改善视神经的修复.

关键词:
生物材料是一种生物材料.神经导管是指导导管的导管.视神经被压碎的情况视神经病变是一种视神经病变.复兴再生是一种再生方式.

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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