老年人营养风险指数与冠状动脉再血管化患者的不良结果的关联:一项队列研究
Beili Xie1, Yue Shi1, Mingwang Liu1
1Cardiovascular Department, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Frontiers in cardiovascular medicine
|January 8, 2025
概括
低老年营养风险指数 (GNRI) 表示的营养状况不佳,与接受冠状动脉再血管化治疗的患者的结果更差有关,包括死亡率更高和住院时间更长.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 营养科学 营养科学
背景情况:
- 营养状况是影响患者结果的关键因素.
- 营养状况对冠状动脉再血管化的结果的影响需要进一步研究.
研究的目的:
- 评估在接受冠状动脉再血管化的患者的基线营养状况和不良结果之间的关联.
- 分析老年营养风险指数 (GNRI) 与死亡率,急性损伤 (AKI) 和住院时间等结果之间的关系.
主要方法:
- 利用MIMIC-IV数据库识别正在进行冠状动脉再血管化的患者.
- 计算了老年营养风险指数 (GNRI) 以将患者分类为营养不良组.
- 采用了Cox的比例危险模型,Kaplan-Meier分析和受限立方线来评估GNRI对结果的影响.
主要成果:
- 较低的GNRI与接受冠状动脉再血管化的患者28天死亡率的增加显著相关.
- 降低的GNRI水平与急性损伤 (AKI) 和延长住院时间的更高发病率相关.
- 低GNRI与死亡率之间的关联在65岁以下的患者中更为明显.
结论:
- 老年营养风险指数 (GNRI) 是接受冠状动脉再血管化的患者的有价值的预后指标.
- 较低的GNRI得分预示着更糟糕的预后,包括更高的死亡率,更高的AKI风险和更长的住院时间.
- 营养评估和干预可能对改善这一患者群体的结果至关重要.
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