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Updated: Jun 3, 2025

Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells
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优化的BCMA/CS1双特异性TRuC-T细胞分泌IL-7和CCL21,可有效控制多发性骨髓瘤

Min Li1, Rong Zheng1,2, Zairu Liu1,3

  • 1Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, China.

Frontiers in immunology
|January 8, 2025
PubMed
概括

优化的T细胞受体融合构造 (TRuC) - - 分泌IL-7和CCL21的T细胞显示出对多发性骨髓瘤的增强疗效. 这些新型BC-7×21 TRuC-T细胞在体内表现出改善的持续性和瘤抑制.

关键词:
这是一种B细胞成熟抗原.在C-C基因基因基因接体21 21CD2子集1 CD2子集1 CD2子集1T细胞受体融合构造 T细胞受体融合构造介质蛋白-7-7的使用方法多发性骨髓瘤是多发性骨髓瘤的一种疾病.

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