隔膜超声波在鉴定COPD患者的萨尔科佩尼亚中的作用:一个横截面研究
Nur Aleyna Yetkin1, Sibel Akın2, Derya Kocaslan2
1Pulmonology Department, Erciyes University Faculty of Medicine, Kayseri, Türkiye.
International journal of chronic obstructive pulmonary disease
|January 8, 2025
概括
隔膜加厚分量 (TF) 可能有助于检测慢性阻塞性肺部疾病 (COPD) 患者的肉症. 这种超声波测量结果显示,它是确定COPD肌肉损失的辅助工具.
科学领域:
- 肺部医学 肺部医学
- 老年病的医生 老年病的医生
- 诊断成像 诊断成像 诊断成像
背景情况:
- 慢性阻塞性肺病 (COPD) 经常与皮症同时发生,影响患者的生活质量和疾病进展.
- 标志着肌肉质量和功能的减少的萨尔科佩尼亚,加剧了COPD症状并增加了住院治疗率.
- 隔膜超声波提供了一种潜在的非侵入性方法来评估COPD患者的肌肉健康.
研究的目的:
- 为了研究隔膜超声波在诊断COPD的个体中鉴定肉症的疗效.
- 探索隔膜功能参数与COPD中肉病的存在之间的关系.
主要方法:
- 进行了一项涉及35名COPD患者 (FEV1 30-80%) 的横截面双盲研究.
- 使用EWGSOP2标准诊断了萨科佩尼亚,评估包括生物电阻分析 (BIA),手握强度和步行速度.
- 隔膜超声波测量出行和厚度,计算正常呼吸和深呼吸 (TLC-TF) 期间的加厚分数 (TF).
主要成果:
- 在研究的COPD患者中,近一半 (48.6%) 被识别为肉.
- 虽然隔膜厚度没有显著差异,但在肉患者中,隔膜厚化分数 (TF和TLC-TF) 显著降低 (p<0.05).
- 隔膜外流接近统计学意义 (p=0.078),最大呼吸压力 (MIP/MEP) 在各组之间没有差异.
结论:
- 隔膜加厚分数 (TF) 显示出作为一种有价值的独立指标,可用于检测COPD患者的肉症.
- 隔膜功能的超声波评估,特别是TF,可以作为辅助诊断措施.
- 建议在更大的队列中进行进一步的研究,以验证膜超声波在COPD中治疗肉症的临床实用性.
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