甲状腺功能低下症:西方和东方国家之间的相似之处和差异
Yu-Ying Yang1,2, Yan-Hua Deng1,2, Li-Hao Sun1,2
1Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
概括
甲状腺功能低下症 (hypoPT) 管理在东方和西方国家之间有相似之处,尽管PTH替代疗法在东方不太常见. 建议进行进一步的比较研究,以获得最佳的患者护理.
科学领域:
- 内分泌学 在内分泌学.
- 比较医学是一种比较医学.
背景情况:
- 甲状腺功能低下症 (hypoPT) 呈现出严重的急性和慢性并发症.
- 现有的hypoPT管理指南主要来自西方国家.
- 缺乏对东方和西方国家的数据进行系统的比较.
研究的目的:
- 为了比较东方和西方国家的流行病学,遗传学,临床表现和 hypoPT 的治疗方法.
- 为了确定这些地区之间的hypoPT管理的相似之处和差异.
主要方法:
- 在PubMed和CNKI数据库中进行全面的文献搜索.
- 包括来自中国,韩国,日本,印度,美国,加拿大和意大利的研究.
- 审查得到了欧洲化组织学会 (ECTS) 董事会的批准.
主要成果:
- 术后的hypoPT是这两个地区的主要形式.
- 在东方和西方人群中,hypoPT的遗传特征和临床特征是可比的.
- 和维生素D类似物是常见的治疗方法;PTH替代疗法在东方国家更难获得.
结论:
- 对于甲状腺结节的手术指南应该强调甲状腺侧腺保护.
- 在hypoPT管理中,持续的东西方合作至关重要.
- 需要对治疗有效性,安全性和经济性进行直接比较研究.
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