转录因子ATF2通过激活PLEKHO1/NUS1通路加速清细胞细胞癌的进展

Zheng Lu1, Jinge Xu2, Junyu Li2

  • 1Gravel Center, Nanyang First People's Hospital, Nanyang, China.

Molecular carcinogenesis
|January 8, 2025
PubMed
概括

激活转录因子2 (ATF2) 激活含有O1 (PLEKHO1) 表达的普莱克斯特林同质域,通过调节核无烯酸铁酸盐合成酶1 (NUS1) 来促进清细胞细胞癌 (ccRCC) 的进展. 这项研究揭示了ccRCC发育中的新型分子机制.

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