离子通过蛋白质体路径诱导Smad2降解,减弱转化生长因子β1诱导的细胞外矩阵积累

Jialin Li1, Jiawen Zhang2, Meng Zhang2

  • 1Department of Traditional Chinese Medicine, Gannan Medical University, Ganzhou, China.

概括

细胞外 (Ca2+) 通过降解Smad2蛋白质来保护,这是纤维化的一个关键因素. 这种作用减少了纤维内素 (FN) 沉积,为病提供了潜在的治疗标.

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