梨状圆盘作为手术后硬化模式变化的风险因素,在变形椎间体融合后发生变化
Yang Xiao1, Wenbin Shuai2, Zhuang Zhang1
1Department of Orthopaedic, Orthopaedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Orthopaedic surgery
|January 8, 2025
概括
梨状圆盘和更高的体重指数 (BMI) 是脊髓融合后手术后硬化模式变化 (MCs) 的独立风险因素. 这些变化与较低的融合率和较差的结果有关.
科学领域:
- 脊柱外科手术 脊柱外科手术
- 放射学 放射学是一门学科.
- 整形外科 整形外科 整形外科
背景情况:
- 梨状圆盘可能会增加脊柱融合过程中末端板损伤的风险.
- 手术后的硬化模式变化 (MCs) 可能来自端板损伤.
- 梨状圆盘与术后硬化性MC之间的关系尚未得到充分证实.
研究的目的:
- 为了调查手术后硬化性MCs的风险因素,经过变形腰间体融合 (TLIF).
- 具体评估梨状圆盘对术后硬化性MC的发生的影响.
- 评估梨状圆盘和相关因素对TLIF后临床结果的影响.
主要方法:
- 对411名接受TLIF治疗的患者 (2018年1月至2022年1月) 的回顾性分析.
- 匹配的病例对照研究比较了50名术后硬化MC患者和50名没有.
- 评估包括VAS,ODI,X射线,CT,MRI;统计分析使用t测试,奇平方和后勤回归.
主要成果:
- 在术后硬化性MCs组中,观察到梨状圆盘 (27对7) 的患病率显著更高.
- 术后硬化性MC的独立风险因素包括梨状圆盘和较高的BMI.
- 患有硬化性MC的患者的融合率较低,子沉降率增加,结果较差.
结论:
- 梨状圆盘形态和高BMI是TLIF后发生术后硬化性MC的重要独立风险因素.
- 术后硬化性MC与脊柱融合减弱,子沉降增加和不太有利的临床症状改善有关.
相关概念视频
Herniated Intervertebral Disc l: Introduction
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease I: Introduction
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Degenerative Disc Disease ll: Pathophysiology
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...


