在一般人群中,肌酸摄入量与患有功能障碍或不患功能障碍的个体的循环环囊素C水平升高无关
David Nedeljkovic1, Sonja Baltic1, Nikola Todorovic1
1Applied Bioenergetics Lab, Faculty of Sport and PE, University of Novi Sad, Novi Sad, Serbia.
Journal of the American Nutrition Association
|January 8, 2025
概括
饮食中的肌酸摄入与脏不良影响无关,即使在患有功能衰竭的人群中也是如此. 这项研究表明,来自食物的肌酸可能是一种保护性营养素,可能有利于脏健康.
科学领域:
- 营养科学 营养科学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
背景情况:
- 食肌酸的安全性,特别是风险人群中的脏健康,在人口层面上仍未得到充分探索.
- 患有先前存在的脏疾病的人可能对食补充剂 (如肌酸) 的影响有独特的担忧.
研究的目的:
- 调查饮食中的肌酸消耗与功能标志物之间的关联.
- 通过使用国家调查数据,在患有功能衰竭和没有功能衰竭的个体中专门研究这种关系.
主要方法:
- 分析了1999-2001年国家健康和营养检查调查 (NHANES) 的数据.
- 包括4969名参与者,测量了血清细胞酸C水平和饮食摄入肌酸的数据.
- 使用线性回归来评估肌酸摄入量和囊素C之间的关联,按脏功能分层.
主要成果:
- 在整个样本中,观察到每日肌酸摄入量和血清囊素C水平之间存在显著的反向关联.
- 每一毫克增加的每日肌酸摄入量对应于0.003 mg/dL的cystatin C的减少.
- 在患有功能障碍的参与者中,较高的肌酸摄入量与较低的cystatin C水平显著相关.
结论:
- 饮食中的肌酸似乎不会对脏健康构成风险,即使是患有功能衰竭的个体.
- 从食物中获得的肌酸可能具有保护性质.
- 研究结果支持将肌酸视为对脏健康有潜在益处的营养素.
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