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在末期病患者中,通过左心室压力-菌株循环对左心室功能进行定量评估

Meihua Chen¹, Bing Li², Jue Lin²

¹Department of Ultrasound Medicine, The Second Affiliated Hospital of Hainan Medical University, Haikou, China, 522395602@qq.com.

|January 8, 2025

概括

左心室压力-应变循环 (LV-PSL) 技术揭示了末期病 (ESRD) 患者的早期心脏变化,包括LV缩和心肌功能受损. 维护血液透析在这些患者中没有显著改变心肌工作量.

科学领域:

心脏病学心脏病学
腎臟病學 (nephrology) 是一種醫學.
生物医学工程生物医学工程

背景情况:

末期病 (ESRD) 与心脏功能障碍有关.
左心室压力-应变循环 (LV-PSL) 是一种新的非侵入性技术,用于评估心肌工作 (MW) 和心脏功能.
在ESRD患者中早期发现心脏变化至关重要.

研究的目的:

在ESRD患者中利用LV-PSL早期检测左心室 (LV) 结构和MW变化.
为了比较接受维持血液透析 (MHD) 的ESRD患者与未接受透析的患者以及健康对照患者之间的心脏功能.

主要方法:

72名ESRD患者被分为透析 (ESRD-D) 和非透析 (ESRD-ND) 组.
30名健康参与者组成了对照 (N) 组.
进行了LV-PSL和传统心声回声,以评估全球纵向应变 (GLS),峰值应变分散 (PSD),全球建设性工作 (GCW),全球浪费工作 (GWW),全球工作指数 (GWI) 和全球工作效率 (GWE).

主要成果:

左心室缩是ESRD患者中最常见的异常.
与对照组相比,ESRD患者的GLS显著降低,PSD较高.
患有ESRD的患者的GWW显著高,GWE低于对照组 (p < 0.05).
两组之间没有观察到GWI和GCW的显著差异 (p > 0.05).
GCW,GWI和GWE与LV喷射分数 (EF) 有正相关,与GLS有负相关.
GWW与LVEF负相关,与GLS和PSD正相关.
GWE显示与PSD的负相关性 (所有p < 0.05).

结论:

在ESRD患者中出现亚临床LV结构和功能异常.
LV-PSL有效地识别这些早期心脏变化.
在ESRD患者中,MHD并没有显著影响心肌工作量.

关键词:

心声回声扫描 (Echocardiography) 是一种心声回声扫描.最终阶段的脏疾病.左心室的功能是没有的.左心室的压力-张力循环.心肌功能的工作.

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