在中风或过渡性缺血性发作患者中,出生地区的药物坚持差异
Monique F Kilkenny1,2, Lachlan L Dalli1, Nadine E Andrew3,4
1School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.
Neuroepidemiology
|January 8, 2025
概括
在中风或过渡性缺血性发作 (TIA) 后的药物坚持因出生地区而异. 出生在其他大洋洲和南亚/中亚地区的个人对关键预防药物的坚持程度较低.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 文化和语言障碍可能会影响医疗质量,包括药物坚持.
- 脑卒中后的药物坚持对于二次预防至关重要.
研究的目的:
- 为了调查是否坚持预防药物根据出生地区在中风/过渡性缺血性发作 (TIA) 幸存者的不同.
- 为了确定与出生地点相关的中风后护理的潜在差异.
主要方法:
- 观察性研究将澳大利亚中风临床注册数据与行政数据 (2012-2016) 联系起来.
- 包括有史以来第一次中风/TIA的成年人,他们在一年内接受了抗高血压,降脂或抗血栓药物.
- 使用多变量逻辑回归来分析依从性 (覆盖日数比例≥80%),调整以人口统计和临床因素.
主要成果:
- 在24,236名参与者中,坚持率为54% (抗高血压药),56% (降脂药) 和49% (抗血栓药).
- 与澳大利亚出生的个人相比,出生在其他大洋洲的参与者对降脂药物 (OR 0.78) 和抗血栓药物 (OR 0.84) 的坚持较低.
- 出生在南亚/中亚的人对降脂药物 (OR 0.76) 和抗血栓药物 (OR 0.55) 的坚持明显较低.
结论:
- 出生地区与中风/TIA后的药物坚持差异有关,特别是来自亚洲和大洋洲的个人.
- 需要有针对性的教育干预措施,以满足这些患者群体的特定需求,并提高患者的坚持.
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