接的Kono-S解剖结合是克罗恩病术后内镜复发的保护因素吗? 一个单一的中心,回顾性队列研究
Tianrun Song1, Yang Chen1, Liqun Wang2
1Department of General Surgery, Center for Inflammatory Bowel Diseases, The Affiliated Jinling Hospital of Nanjing Medical University, Nanjing, China.
概括
接的Kono-S解剖切除对于克罗恩病患者来说是安全的. 虽然它并不能绝对防止复发,但与传统方法相比,它显示出较低率的趋势.
科学领域:
- 胃肠病学 胃肠病学
- 手术创新 在外科创新.
- 炎症性肠道疾病研究研究
背景情况:
- 手工的Kono-S解已被确定为克罗恩氏病 (CD) 患者的安全,减少术后复发 (POR).
- 调查接的Kono-S解剖结合为CD肠道解剖结合手术提供了潜在的优势.
研究的目的:
- 为了评估接Kono-S解体在克罗恩病患者接受肠道解体的好处.
- 关于复发和结果,要比较接的Kono-S解与常规接的侧对侧解.
主要方法:
- 审查了一份前性地维护的CD患者的数据库,这些患者经历了肠道解.
- 患者被分为传统的接侧向接和接Kono-S接组.
- 修改后内镜复发 (mER) 是主要终点,其次要终点包括内镜复发 (ER),严重的ER和术后结果.
主要成果:
- 与传统方法相比,接的Kono-S解与较低的mER (12.7%vs25.4%),ER (20.6%vs28.6%) 和严重的ER (6.3%vs11.1%) 相关.
- 多变量分析确定了接的Kono-S解作为mER的独立保护因子 (OR,0.35;P =.047).
- 男性性别和BMI<18.5 kg/m2被确定为mER的独立风险因素.
结论:
- 接的Kono-S解剖切除是克罗恩病患者的安全手术选择.
- 虽然显示出减少复发的趋势,但与传统方法相比,接的Kono-S解剖并没有显著证明它是预防术后复发的保护因素.
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