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Updated: Jun 3, 2025

In Vitro Directed Evolution of a Restriction Endonuclease with More Stringent Specificity
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In Vitro Directed Evolution of a Restriction Endonuclease with More Stringent Specificity

Published on: March 25, 2020

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在动物和植物AP内核酶中对立的基因特异性和单链DNA活性的不同演变

Marina Jordano-Raya1,2,3,4, Carol E Schrader4, Rafael R Ariza1,2,3

  • 1Maimónides Biomedical Research Institute of Córdoba (IMIBIC), Avda. Menéndez Pidal s/n, Córdoba 14004, Spain.

Nucleic acids research
|January 8, 2025
PubMed
概括

人类和植物AP内核酶因关键氨基酸变异而在DNA修复活动上有所不同. 交换这些残留物改变了酶的特异性,揭示了对DNA修复进化的洞察力.

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相关概念视频

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Homologous Recombination

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