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Updated: Jun 3, 2025

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外基因生成的Hsa_Circ_0000116通过PI3K/Akt/mTOR和p38/MAPK通路促进骨肉瘤细胞恶性

Chunsheng Gao1, Xiaowei Wang1, Huichao Yan1

  • 1Department of Orthopaedics, The Third People's Hospital of Hubei Province, Wuhan, China.

DNA and cell biology
|January 8, 2025
PubMed
概括

携带圆形RNA hsa_circ_0000116的外体细胞促进骨髓瘤 (OS) 的进展. 沉默这个circRNA通过影响PI3K/Akt/mTOR和p38/MAPK通路来抑制OS细胞恶性瘤,提供潜在的治疗点.

关键词:
圆形的RNARNA是一个圆形的RNA.外基因组是外基因组的组成部分.骨质肉瘤是骨质肉瘤的一种疾病.p38 基因激活蛋白激酶的作用酸-3-酶/蛋白酶B/哺乳动物目标的拉巴胺.

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