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Updated: Jun 3, 2025

Author Spotlight: Advancing Techniques and Discoveries in Protein Synthesis and Assembly Through Innovative Mitochondrial Research
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在线粒体复合体IV组装的早期阶段,COA5具有至关重要的作用

Jia Xin Tang1, Alfredo Cabrera-Orefice2, Jana Meisterknecht2

  • 1Mitochondrial Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.

Life science alliance
|January 8, 2025
PubMed
概括

细胞染色体c氧化酶组合因子5 (COA5) 中的致病变体通过损害复杂IV组合而导致线粒体疾病. 这项研究揭示了COA5对于复杂IV中MTCO2亚单元的早期生物发生至关重要.

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