干细胞疗法作为对迪斯科原性腰部疼痛的治疗方法:系统性审查
Randy Randy1, Khandar Yosua2, Aswin Guntara3
1Emergency Department, Mayapada Hospital Kuningan, Jakarta, Indonesia dr.randysamsul@gmail.com.
International journal of spine surgery
|January 8, 2025
概括
干细胞疗法可显著改善慢性迪斯科原性腰部疼痛 (LBP). 这种治疗改善了日常生活活动并减少了疼痛,为LBP患者提供了有前途的选择.
科学领域:
- 再生医学是一种再生医学.
- 整形外科 整形外科 整形外科
- 疼痛管理 疼痛管理
背景情况:
- 腰部疼痛 (LBP) 影响了80%的人口,而光盘性疼痛是常见的原因.
- 慢性LBP可以导致严重的残疾.
- 对于LBP的传统治疗方法范围从保守到手术干预.
研究的目的:
- 为了评估干细胞疗法对迪斯科原性腰部疼痛的疗效.
- 评估干细胞治疗对疼痛和功能结果的影响.
主要方法:
- 对PubMed和ScienceDirect研究的系统审查,截至2023年9月.
- 在8篇文章中分析了283例光盘性LBP病例的临床结果.
- 使用视觉模拟尺度 (VAS) 测量疼痛,并通过奥斯韦斯特里残疾指数 (ODI) 测量功能状态.
主要成果:
- 干细胞治疗在ODI和VAS得分上显示出显著的改善 (P < 0.00001).
- 在治疗后观察到Pfirrmann等级的显著改善 (P = 0.005).
- 对骨髓吸附度的亚组分析也显示了ODI和VAS的显著减少 (P < 0.00001).
结论:
- 内干细胞疗法是一种可行的治疗选择,用于迪斯科基性LBP.
- 该疗法有效地改善疼痛,并增强日常生活活动.
- 干细胞治疗为治疗慢性腰部疼痛提供了一个有希望的替代方案.
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