在暴露前预防 (PrEP) 的系统审查中评估股权报告
Bethany Paris1, Kelsi Batioja2, Vanessa Lin2
1Oklahoma State University College of Osteopathic Medicine, Tulsa, Oklahoma, USA bparis@okstate.edu.
Sexually transmitted infections
|January 8, 2025
概括
对艾滋病毒暴露前预防 (PrEP) 的系统性审查往往忽视了关键的健康公平标准. 改善关于种族和社会经济地位等因素的报告可以提高PrEP获取和艾滋病毒预防策略.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 健康 公平 研究 健康 公平 研究
背景情况:
- 艾滋病毒暴露前预防 (PrEP) 对于减少艾滋病毒传播至关重要.
- 由于艾滋病毒对少数群体的不成比例影响,健康公平是一个重大问题.
- 在对PrEP的系统审查中评估公平性报告对于了解进入障碍至关重要.
研究的目的:
- 评估在暴露前预防 (PrEP) 的系统审查和元分析 (SRMA) 中报告的健康公平领域.
- 利用 PROGRESS Plus 框架来评估 PrEP 研究中股权报告的全面性.
- 识别可能阻碍PrEP使用的报告缺口,并为改进的艾滋病毒预防策略提供信息.
主要方法:
- 在PubMed,Embase和Cochrane数据库中对PrEP使用的SRMA进行了系统的文献搜索.
- 应用了PROGRESS Plus框架来提取关于公平领域的数据:居住地,种族/种族/文化/语言,职业,性别/性别,宗教,教育,社会经济地位,社会资本,年龄和残疾.
- 分析了36个选定的SRMA,以包含和报告这些股权领域和子集团分析.
主要成果:
- 在36个SRMA中,只有5.6%报告遵守了股权框架; 66.7%是在美国进行的.
- 居住地和性别/性别是最常见的 (34/36项研究),其次是年龄 (83.3%) 和种族/种族 (66.7%).
- 最少报告的是宗教 (0%) 和残疾 (2.8%);52.78%的SRMA没有对股权领域进行子组分析.
结论:
- 关于HIV PrEP的SRM通常报告性别/性别和年龄,但经常忽视其他关键的公平标准.
- 为了解决利用障碍,需要加强PrEP SRMA中的PROGRESS Plus项目报告.
- 改善公平报告可以显著提高艾滋病毒预防策略的有效性,并减少健康差异.
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