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Updated: Jul 29, 2026

Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark
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未定位的代谢学揭示了希斯H3K27脱甲基酶UTX与神经发育之间的代谢联系

Lin Chen1, Maozhu Liu2, Xinhua Dai3

  • 1Department of Pharmacy, Chongqing Health Center for Women and Children, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.

Journal of cellular and molecular medicine
|January 8, 2025
PubMed
概括

染色体修饰剂UTX (X染色体上无处不在的四基重复) 对于神经发育至关重要. 缺少它会导致神经元细胞死亡和记忆障碍,与改变的氨酸,酸盐和谷氨酸代谢有关.

关键词:
UTX UTX UTX UTX UTX UTX是什么意思代谢途径的代谢途径代谢生物组的代谢生物组神经发育的神经发育

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相关概念视频

Position-effect Variegation02:32

Position-effect Variegation

In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.