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Updated: Jun 3, 2025

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PARP1 抑制剂的临床应用和癌症治疗中的挑战

Yunlin Luo1, Mingcheng Nie1, Yuekang Chen1

  • 1Cancer Research Center, Shantou University Medical College, Shantou 515041, Guangdong, PR China.

Current cancer drug targets
|January 8, 2025
PubMed
概括

聚分子酶1 (PARP1) 抑制剂通过向DNA修复,在癌症治疗中表现有前途. 本综述详细介绍了它们的机制,临床用途以及治疗各种癌症的挑战.

关键词:
在 PARP 抑制剂.PARP1 的第一部分这是一种PARylation.癌症治疗疗法 癌症治疗药物耐药性. 药物耐药性.这就是Olaparib.

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