与乙性食道炎相关的食物影响:不同的人口统计,干预措施和有希望的预测模型
Yichen Wang1, Yuting Huang2, Yee Hui Yeo3
1Division of Hospital Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Digestive diseases and sciences
|January 8, 2025
概括
性食道炎 (EoE) 是越来越多的食物损失的原因. 机器学习模型可以帮助识别需要活检的患者,改善这种疾病的诊断.
科学领域:
- 胃肠病学 胃肠病学
- 过敏和免疫学 过敏和免疫学
- 数据科学在医学中的数据科学
背景情况:
- 性食道炎 (EoE) 是造成食物损失的重要原因之一,而且日益增加.
- 了解与 EoE 相关的食物影响的特征对于诊断和管理至关重要.
研究的目的:
- 在患有和没有EoE的患者中对食物影响进行全国性的分析.
- 在食品影响病例中确定与EoE相关的人口统计,并发病和干预模式.
- 开发和评估机器学习模型,用于预测食物影响患者的EoE.
主要方法:
- 全国紧急情况部门样本数据 (2018-2019) 的回顾性分析.
- 对有或没有EoE诊断的食物影响患者进行比较.
- 开发使用ICD代码预测EoE的机器学习模型.
主要成果:
- 在146,084例食物影响病例中,4.9%的患者同时被诊断为EoE.
- 患有EoE的患者是年轻的男性,并发症较少,但肥胖,喘,胃炎和过敏性鼻炎的发病率较高.
- 在EoE患者中,食管胃管腺镜 (89.6%与51.1%) 和活检 (54.9%与13.4%) 的比例显著增加.
- 机器学习模型实现了86.1%的灵敏度,EoE预测的AUC为0.828.
结论:
- 与EoE相关的食物影响表现出不同的人口统计和并发病概况.
- 机器学习模型显示出作为有效查工具的潜力,用于识别食物影响患者的EoE.
- 这些模型可以帮助临床医生决定何时进行EOE诊断的活检.
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