使用倾向性得分匹配对单侧和双侧乳腺癌之间的生存率进行比较:回顾性单中心分析
Talar Ozler1, Rusen Cosar2, Necdet Sut3
1Department of Radiation Oncology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Breast cancer research and treatment
|January 8, 2025
概括
同步双边乳腺癌 (SBBC) 患者的存活率最低,即使有积极的治疗方法. 这表明SBBC是生存的明显不良预后因素.
科学领域:
- 在瘤学瘤学.
- 乳腺癌研究研究 乳腺癌研究
- 临床结果 临床结果
背景情况:
- 区分单边和双边乳腺癌对于了解疾病特征至关重要.
- 单边和双边乳腺癌病例之间的生存率和治疗疗效可能会显著不同.
研究的目的:
- 为了比较单边和双边乳腺癌之间的患者特征和生存结果.
- 为了确定这些群体之间的无病生存率和总生存率的差异.
主要方法:
- 一项回顾性研究包括1947名患有侵袭性乳腺癌的患者.
- 患者被分为单边 (96.4%) 和双边 (3.6%) 的乳腺癌组.
- 双边病例进一步被分类为同步 (n=24) 或超时 (n=47).
主要成果:
- 同步双边乳腺癌 (SBBC) 的总生存 (OS) 持续时间最低.
- 在SBBC和甲时双边乳腺癌 (MBCC) 之间观察到一个统计学上显著的OS差异.
- 这种SBBC的生存差异与单边乳腺癌 (p=0.027) 的生存差异相似.
结论:
- 与其他乳腺癌类型相比,同步双边乳腺癌 (SBBC) 的预后较差.
- 尽管接受了更积极的治疗,但SBBC患者的生存率最低.
- 应承认SBBC是患者生存的独立不良预后因素.
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