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在大麻素1受体上THC模拟活性的结构基础

Thor S Thorsen1,2, Yashraj Kulkarni1, David A Sykes3,4

  • 1Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.

Nature communications
|January 8, 2025
PubMed
概括

研究人员绘制了与THC类似物结合的大麻素受体1 (CB1) 的结构. 这揭示了四大麻素 (THC) 和类似化合物如何与CB1相互作用,影响信号和药物设计.

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