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吸烟和腹部肥胖之间的相互作用对糖尿病前期的影响
Huali Xiong1,2, Peng Zhao3, Fengxun Ma4
1Center for mental health of Rongchang District, Chongqing, China.
吸烟和腹部肥胖在中国农村成年人中显著增加糖尿病前期风险. 它们的综合效应显示出强烈的协同作用,突出了关键的公共卫生问题.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 代谢疾病 代谢疾病
背景情况:
- 糖尿病前期 (PDM) 是一个日益严重的全球健康挑战.
- 关于吸烟和腹部肥胖对中国农村人口PDM风险的综合影响的研究有限.
研究的目的:
- 研究吸烟和腹部肥胖对中国西南部农村成年人PDM风险的独立和互动影响.
主要方法:
- 在中国西南部荣区,对3017名成年人 (40-79岁) 进行了横截面调查.
- 使用多变量逻辑回归来评估风险因素和相互作用 (乘法和加法).
- 使用因相互作用 (RERI),可归因比例 (AP) 和协同指数 (SI) 的相对过度风险来量化相互作用.
主要成果:
- 在PDM的患病率为38.98%.
- 当前吸烟 (OR=1.26) 和腹部肥胖 (OR=1.4) 独立地与增加PDM风险有关.
- 在目前的吸烟和腹部肥胖之间发现了显著的附加相互作用 (OR=3.56),AP=0.59和SI=5.51,表明强烈的协同效应.
结论:
- 目前的吸烟和腹部肥胖在这个人群中协同增加糖尿病前期风险.
- 针对戒烟和减肥的公共卫生战略对于中国农村的PDM预防至关重要.
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