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Updated: Jun 3, 2025

Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay
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内皮细胞尖端的位置,状体的形成和生物力学都需要BMPR2的表达和信号传递

Christian Hiepen1,2, Mounir Benamar3, Jorge Barrasa-Fano4

  • 1Freie Universität Berlin, Institute for Chemistry and Biochemistry, Thielallee 63, 14195, Berlin, Germany. christian.hiepen@w-hs.de.

Communications biology
|January 8, 2025
PubMed
概括

骨形态遗传蛋白质受体2 (BMPR2) 在血管发芽过程中对内皮细胞尖端细胞 filopodia 的形成和迁移至关重要. 失去BMPR2会影响细胞机制和尖端细胞行为,从而损害血管生成.

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