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Updated: Jun 3, 2025

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通过调节γ-分泌酶,EBP1增强了粉样β病理

Byeong-Seong Kim1,2, Inwoo Hwang1,2, Hyo Rim Ko1,2

  • 1Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Korea.

Nature aging
|January 8, 2025
PubMed
概括

在阿尔茨海默病 (AD) 中,ErbB3结合蛋白1 (EBP1) 抑制了粉样β (Aβ) 的产生. EBP1的裂变加速了Aβ沉积和认知衰退,这表明EBP1的保存是潜在的AD疗法.

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