在患有活跃和不活跃结性脊柱炎的患者中,前后眼部变化
Yücel Karakurt1, Nurdagül Aktaş2, Ahmet Mehmet Somuncu3
1Deparment of Ophthalmology, Faculty of Medicine, Erzincan Binali Yıldırım University, Erzincan, Turkey.
概括
结节性脊柱炎 (AS) 即使没有脑膜炎,也会导致眼睛的变化,包括角膜和胸膜. 这项研究强调了对AS患者进行仔细的眼科评估和随访的必要性.
科学领域:
- 眼科医生 眼科 眼科
- 类风湿病学 类风湿病学
- 角质科学 角质科学
背景情况:
- 化脊柱炎 (AS) 是一种慢性炎症性疾病.
- 浴结节脊柱炎疾病活动指数 (BASDAI) 评估AS疾病活动.
- 在AS中,眼部表现很常见,但前后段变化需要进一步调查.
研究的目的:
- 评估结性脊柱炎 (AS) 患者的前部和后部眼部变化.
- 根据BASDAI分数,比较活跃和不活跃的AS组之间的眼睛发现.
- 评估角膜参数,眼膜稳定性和AS患者的胸膜厚度.
主要方法:
- 78名AS患者和70名对照人群接受了全面的眼科检查.
- AS患者被分为活跃 (BASDAI ≥4) 和不活跃 (BASDAI <4) 组.
- 评估的参数包括内皮细胞密度,角膜厚度,撕裂时间和胸膜厚度.
主要成果:
- 与对照组相比,AS患者的内皮细胞密度和六角性下降,角膜细胞变异和大小增加,角膜厚度减少.
- 撕裂时间和希尔默测试结果较低,而AS患者的眼表面疾病指数得分较高.
- 在多个测量点上,AS患者的胸膜厚度显著增加.
结论:
- 结性脊柱炎与明显的前后眼部变化有关,独立于疾病活动水平.
- 这些眼部变化甚至可以在没有临床诊断的脑膜炎的情况下发生.
- 对AS患者来说,对眼科评估和随访的注意力增加至关重要,特别是在眼科手术方面.
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